What causes pulmonary alveolar proteinosis?
The cause of pulmonary alveolar proteinosis is unknown. In some people, however, it appears to result from infection, immune deficiency, or from exposure to silica, aluminum oxide, and a variety of dusts and fumes. In some cases, it is associated with infection or immune deficiency. Occasionally, it is related to exposure to toxic substances, such as inorganic dusts, infection with pneumocystis carinii, certain cancers, and immunosuppressant drugs. The disease generally affects people between the ages of 20 and 60 who have not previously had lung disease. |