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What causes pulmonary alveolar proteinosis?

The cause of pulmonary alveolar proteinosis is unknown. In some people, however, it appears to result from infection, immune deficiency, or from exposure to silica, aluminum oxide, and a variety of dusts and fumes. In some cases, it is associated with infection or immune deficiency. Occasionally, it is related to exposure to toxic substances, such as inorganic dusts, infection with pneumocystis carinii, certain cancers, and immunosuppressant drugs. The disease generally affects people between the ages of 20 and 60 who have not previously had lung disease.

 

More information on pulmonary alveolar proteinosis

What is pulmonary alveolar proteinosis? - Pulmonary alveolar proteinosis (PAP) is a rare lung disorder in which the tiny air sacs of the lungs fill up with a secreted material known as surfactant.
What causes pulmonary alveolar proteinosis? - The cause of pulmonary alveolar proteinosis is unknown. It appears to result from infection, immune deficiency, or from exposure to silica.
What're the symptoms of pulmonary alveolar proteinosis? - Symptoms of pulmonary alveolar proteinosis include mild shortness of breath associated with a nonproductive or minimally productive cough, weight loss.
How is pulmonary alveolar proteinosis diagnosed? - Pulmonary function tests may show restrictive lung disease and abnormal diffusion.
What's the treatment for pulmonary alveolar proteinosis? - The only treatment for pulmonary alveolar proteinosis is removal of the excessive surfactant material from the alveoli.
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