health care  
 
All about lymphangioleiomyomatosis (LAM) causes of lymphangioleiomyomatosis symptoms of lymphangioleiomyomatosis diagnosis of lymphangioleiomyomatosis treatment for lymphangioleiomyomatosis

What causes lymphangioleiomyomatosis (LAM)?

Lymphangioleiomyomatosis can occur in association with tuberous sclerosis due to mutations in the tuberous sclerosis complex (TSC) genes TSC1 or TSC2 genes. Sporadic (isolated) caes of LAM typically result from 2 somatic mutations in the TSC2 gene, although a fraction of sporadic LAM is caused by germline mutations in the TSC1 gene. Smooth-muscle proliferation may obstruct bronchioles, possibly leading to airflow obstruction, air trapping, formation of bullae, and pneumothoraces. Obstruction of lymphatics may result in chylothorax and chylous ascites. Obstruction of venules may result in hemosiderosis and hemoptysis. Excessive proteolytic activity, which relates to an imbalance of the elastase/alpha1-antitrypsin system or metalloprotease and their inhibitors (tissue inhibitors of metalloproteases) may be important in lung destruction and formation of cystlike lesions.
Editor's advice: Avoid nutrient deficiencies and imbalances!

Did you know? It is now estimated that 80-90% of all diseases is related to nutrient deficiencies. Xtend-Life Micro-Nutriments are elite specialty natural products using the latest scientific research and the most up-to-date technology to deliver the greatest possible benefits to you. Its flagship product, Total Balance, provides a broad spectrum of around 80 of the nutrients that provide an overall protection of your vital body systems and organs against degenerative, acute and chronic disease. These nutrients include vitamins, minerals, trace elements, antioxidants, amino acids, neuronutrients, bioflavonoids, carotenoids, herbal extracts, enzymes and other complementary co-factor ingredients. Click here to find more natural health products from Xtend-Life.

Featured health supplements stores

 

More information on lymphangioleiomyomatosis (LAM)

What is lymphangioleiomyomatosis (LAM)? - Lymphangioleiomyomatosis is a rare disorder of unknown etiology characterized by an unusual type of muscle cell that invades the tissues of the lungs.
What causes lymphangioleiomyomatosis? - Lymphangioleiomyomatosis can occur in association with tuberous sclerosis due to mutations in the tuberous sclerosis complex (TSC) genes.
What're the symptoms of lymphangioleiomyomatosis? - Symptoms of lymphangioleiomyomatosis may include shortness of breath, difficulty breathing and coughing.
How is lymphangioleiomyomatosis diagnosed? - The diagnosis of lymphangioleiomyomatosis can be difficult because the early symptoms are similar to those of other lung diseases.
What's the treatment for lymphangioleiomyomatosis? - Therapeutic treatments for lymphangioleiomyomatosis have focused on reducing the production or effects of estrogen.
Respiratory & lung diseases Mainpage

Topics in respiratory and lung diseases

Lung diseases
Occupational lung diseases
Asthma
Respiratory infections
Respiration disorders
Broncheal diseases
Pleural diseases
Lung transplant
 

Featured articles on respiratory and lung diseases

COPD (Chronic obstructive pulmonary disease)
Emphysema
Asbestosis
Lung cancer
Mesothelioma
Silicosis
Pulmonary hypertension
Cystic fibrosis
Severe acute respiratory syndrome (SARS)
Influenza
Bronchitis
Pneumonia

All information is intended for reference only. Please consult your physician for accurate medical advices and treatment. Copyright 2005, health-cares.net, all rights reserved. Last update: July 18, 2005